Chapter 17 THE INDUCTION OF β - LACTAMASES IN EUBACTERIA
نویسندگان
چکیده
The production of a β-lactamase can be induced by the presence of a β-lactam in the culture medium. Three distinct mechanisms have been discovered. In Bacillus licheniformis and Staphylococcus aureus, a penicillin receptor whose properties are similar to those of a PBP detects the presence of the antibiotic. In Citrobacter freundii, the damage caused by β-lactams to the peptidoglycan is detected by an intracellular protein and a similar system might prevail in Streptomyces cacaoi. Finally, in Aeromonas sp regulation involves a two-component system.
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